IV COMPATIBILITY

The System calculates Y-Site Compatibility based on Trissel's Tables®. Each drug entered in the IV Drug Profile is calculated once as the base drug.

Calculation results are shown for the following diluents:

  • D5W
  • NS
  • D5 1/2NS
  • SWFI

Using our scenario for Mr. Ross as the example, the first table displayed in the calculation would show Heparin Sodium as the base drug:

Definitions of the Compatibility Codes are always displayed with the calculations, after the last table. Codes and descriptions have been included here, for your reference.

Compatibility Codes
 Description

NT

 Not Tested
C
 Compatible
C* Although physically compatible, literature reports indicate activity of aminoglycoside antibiotics may be impaired by beta-lactam antibiotics
D Incompatible in the Diluent
I Incompatible
Ic Literature reports indicate that the combination is chemically incompatible
NC Not determined

It is important to note that when no data or conflicting data is reported, the drug combination should be considered incompatible.

Based on the results shown above, you would most likely decide that a second line would be necessary to administer Mr. Ross' gentamicin dose. If heparin and ampicillin are co-administered, note that Normal Saline (NS) should be the Diluent used. Check the Gold Standard Multimedia® IV Admixture Information which follows the Trissel's Tables to verify your decision.

The following three tables are displayed after the heparin table for Mr. Ross:

These tables provide compatibility data if other medications are chosen as the base drug.

Select Next to continue.